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CS-W001157 4
Total: USD 88.00

HCV-IN-47

  • CAS No. 300543-56-0

  • Cat. No. CS-0156606
  • Purity≥97%
  • MDL No.MFCD11519277

*For research and further manufacturing use only, not for direct human use.

HCV-IN-47|CS-0156606

Structure of 300543-56-0

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General Information

  • CAS No. 300543-56-0
  • Cat. No. CS-0156606
  • Purity ≥97%
  • MDL No. MFCD11519277
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₁₉ClN₂
  • Molecular Weight 286.80
  • Synonym(s) None
  • SMILES ClC(C=C1)=CC=C1[C@H](N2CCNCC2)C3=CC=CC=C3

Application

HCV-IN-47 serves as a well-defined, bench-stable scaffold for the synthesis of hepatitis C virus (HCV) protease inhibitors. It features a central heterocyclic core with defined functional group tolerance, enabling straightforward derivatization via standard coupling reactions. The compound facilitates rapid access to diverse analogs in medicinal chemistry campaigns, supporting efficient structure-activity relationship (SAR) exploration through reliable reaction outcomes and straightforward purification.

Synthesis

  • Route1
    • null|null
      943987-59-5
    • ~92%
    • In-stock
      HCV-IN-47|CS-0156606
      300543-56-0

    References

    • DR. REDDY'S LABORATORIES LTD.; DR. REDDY'S LABORATORIES, INC.; RAMAYYA, Vaddadi Pattabhi Patent: WO2009/62036 A2, 2009 ; Location in patent: Page/Page column 21-22 ;
  • Route2
    • null|null
      1092460-01-9
    • ~%
    • In-stock
      HCV-IN-47|CS-0156606
      300543-56-0

    References

    • US2009/281318 A1, ; Page/Page column 3 ;
  • Route3
    • null|null
      1228582-98-6
    • ~%
    • In-stock
      HCV-IN-47|CS-0156606
      300543-56-0

    References

    • US2010/145049 A1, ; Page/Page column 8-9 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   15.27
  • LogP   3.3346
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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