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CS-W001157 4
Total: USD 88.00

(R)-2-((tert-Butoxycarbonyl)amino)-3-(tert-butyldisulfanyl)propanoic acid

  • CAS No. 30044-61-2

  • Cat. No. CS-W013961
  • Purity≥98%
  • MDL No.MFCD00084687

*For research and further manufacturing use only, not for direct human use.

(R)-2-((tert-Butoxycarbonyl)amino)-3-(tert-butyldisulfanyl)propanoic acid|CS-W013961

Structure of 30044-61-2

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General Information

  • CAS No. 30044-61-2
  • Cat. No. CS-W013961
  • Purity ≥98%
  • MDL No. MFCD00084687
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₃NO₄S₂
  • Molecular Weight 309.45
  • Synonym(s) Boc-Cys(StBu)-OH
  • SMILES O=C(O)[C@H](CSSC(C)(C)C)NC(OC(C)(C)C)=O

Description

This chiral building block features a protected amino group and a sterically hindered tert-butyl disulfide moiety, enabling stable incorporation into peptide conjugates. The pendant disulfide facilitates redox-responsive linkage design in bioconjugation workflows.

Synthesis

  • Route1
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • S-tert-Butylmercapto-L-cysteine|CS-0201588
      30044-51-0
    • ~82%
    • In-stock
      (R)-2-((tert-Butoxycarbonyl)amino)-3-(tert-butyldisulfanyl)propanoic acid|CS-W013961
      30044-61-2

    References

    • Debethune, Laurent; Marchan, Vicente; Fabregas, Gemma; Pedroso, Enrique; Grandas, Anna Tetrahedron, 2002 , vol. 58, # 34 p. 6965 - 6978

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   3.1442
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   5

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