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CS-W001157 4
Total: USD 88.00

(2R,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid

  • CAS No. 200184-87-8

  • Cat. No. CS-0435059
  • Purity≥98%
  • MDL No.MFCD22418970

*For research and further manufacturing use only, not for direct human use.

(2R,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid|CS-0435059

Structure of 200184-87-8

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General Information

  • CAS No. 200184-87-8
  • Cat. No. CS-0435059
  • Purity ≥98%
  • MDL No. MFCD22418970
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₅
  • Molecular Weight 245.27
  • Synonym(s) cis-Boc-4-methoxy-D-proline
  • SMILES O=C(N1[C@@H](C(O)=O)C[C@@H](OC)C1)OC(C)(C)C

Synthesis

  • Route1
    • 1-(tert-Butyl) 2-methyl (2R,4R)-4-methoxypyrrolidine-1,2-dicarboxylate|CS-0608720
      200184-86-7
    • ~86%
    • In-stock
      (2R,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid|CS-0435059
      200184-87-8

    References

    • ASTRAZENECA AB; ASTRAZENEKA UK LIMITED Patent: WO2005/26156 A1, 2005 ; Location in patent: Page/Page column 103 ; WO 2005/026156 A1
  • Route2
    • In-stock
      N-Boc-cis-4-Hydroxy-D-proline|CS-W002887
      135042-12-5
    • null|null
      74-88-4
    • ~95%
    • In-stock
      (2R,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid|CS-0435059
      200184-87-8

    References

    • WARNER-LAMBERT COMPANY LLC Patent: WO2006/100565 A1, 2006 ; Location in patent: Page/Page column 14-15 ; WO 2006/100565 A1
  • Route3

    References

    • BOEHRINGER INGELHEIM INTERNATIONAL GMBH Patent: US2011/269737 A1, 2011 ; US 20110269737 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   76.07
  • LogP   1.0954
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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