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CS-W001157 4
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5-Methyl-1,3,4-thiadiazole-2(3H)-thione

  • CAS No. 29490-19-5

  • Cat. No. CS-W013406
  • Purity≥98%
  • MDL No.MFCD00038349

*For research and further manufacturing use only, not for direct human use.

5-Methyl-1,3,4-thiadiazole-2(3H)-thione|CS-W013406

Structure of 29490-19-5

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General Information

  • CAS No. 29490-19-5
  • Cat. No. CS-W013406
  • Purity ≥98%
  • MDL No. MFCD00038349
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₄N₂S₂
  • Molecular Weight 132.21
  • Synonym(s) 5-Methyl-1,3,4-thiadiazole-2-thiol
  • SMILES S=C1SC(C)=NN1

Description

L--phosphatidylcholine (Soy)is anaturally occurring phospholipid and the most abundant phospholipid in eukaryotic cellular membrane with high amount of PUFAs.Soy PC may be used for the synthesis of proteoliposomes, lipoprotein particle (LLP) mimics and flexible liposome (FLUV).

Application

5-Methyl-1,3,4-thiadiazole-2(3H)-thione serves as a versatile heterocyclic building block in medicinal chemistry and materials science. Its thione functionality enables reliable metal coordination and nucleophilic reactivity, while the methyl substituent enhances solubility and metabolic stability. The scaffold exhibits bench stability and compatibility with standard coupling reactions, facilitating efficient synthesis of functionalized derivatives for API development and catalyst design.

Synthesis

  • Route1
    • null|null
      75-15-0
    • null|null
      108-24-7
    • In-stock
      Thiosemicarbazide|CS-0008325
      79-19-6
    • ~%
    • In-stock
      5-Methyl-1,3,4-thiadiazole-2(3H)-thione|CS-W013406
      29490-19-5

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 13 p. 3723 - 3727
  • Route2

    References

    • US3946000 A1, ;
  • Route3
    • Cefazolin Impurity 17|CS-0914698
      38509-92-1
    • ~%
    • In-stock
      5-Methyl-1,3,4-thiadiazole-2(3H)-thione|CS-W013406
      29490-19-5

    References

    • Journal of Heterocyclic Chemistry, , vol. 47, # 4 p. 838 - 845

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   1.50911
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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