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CS-W001157 4
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Tert-butyl (3-amino-2,2-dimethylpropyl)carbamate

  • CAS No. 292606-35-0

  • Cat. No. CS-0179426
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Tert-butyl (3-amino-2,2-dimethylpropyl)carbamate|CS-0179426

Structure of 292606-35-0

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General Information

  • CAS No. 292606-35-0
  • Cat. No. CS-0179426
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₂N₂O₂
  • Molecular Weight 202.29
  • Synonym(s) N-Boc-2,2-dimethyl-1,3-propanediamine
  • SMILES O=C(OC(C)(C)C)NCC(C)(C)CN

Description

Tert-butyl (3-amino-2,2-dimethylpropyl)carbamate serves as a stable, moisture-tolerant amino-protecting group for sensitive amine intermediates. This carbamate derivative features a sterically hindered tert-butyl moiety that enhances stability during purification and storage. The pendant primary amine enables straightforward deprotection under mild acidic conditions, facilitating seamless integration into peptide synthesis and medicinal chemistry workflows.

Application

Tert-butyl (3-amino-2,2-dimethylpropyl)carbamate serves as a stable, bench-friendly amino protecting group for primary amines, enabling selective functionalization in peptide synthesis and medicinal chemistry. Its tert-butyl carbamate moiety facilitates mild acid-mediated deprotection under standard conditions, while the bulky dimethylpropyl scaffold enhances steric protection and minimizes side reactions. The compound exhibits excellent solubility in common organic solvents and compatibility with diverse reaction conditions, making it a reliable building block for complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   1.496
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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