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CS-W001157 4
Total: USD 88.00

Boc-Phg-OH

  • CAS No. 2900-27-8

  • Cat. No. CS-W012629
  • Purity≥98%
  • MDL No.MFCD00065588

*For research and further manufacturing use only, not for direct human use.

Boc-Phg-OH|CS-W012629

Structure of 2900-27-8

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General Information

  • CAS No. 2900-27-8
  • Cat. No. CS-W012629
  • Purity ≥98%
  • MDL No. MFCD00065588
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₇NO₄
  • Molecular Weight None
  • Synonym(s) None
  • SMILES O=C(O)[C@@H](NC(OC(C)(C)C)=O)C1=CC=CC=C1

Description

Boc-Phg-OH serves as a protected phenylglycine derivative for peptide synthesis, featuring a tert-butoxycarbonyl group that ensures stability during handling and reaction. This orthogonal protecting group enables selective deprotection in complex sequences, facilitating efficient incorporation of phenylglycine into target peptides under standard conditions.

Synthesis

  • Route1

    References

    • Bodas, Mandar S.; Upadhyay, Puspesh K.; Kumar, Pradeep Tetrahedron Letters, 2004 , vol. 45, # 5 p. 987 - 988
  • Route2

    References

    • J. Uriach and Cia, S.A. Patent: US5420131 A1, 1995 ; US 5420131 A
  • Route3
    • null|null
      1021948-09-3
    • ~99%
    • In-stock
      Boc-Phg-OH|CS-W012629
      2900-27-8

    References

    • Arosio, Dario; Caligiuri, Antonio; D'Arrigo, Paola; Pedrocchi-Fantoni, Giuseppe; Rossi, Cristina; Saraceno, Caterina; Servi, Stefano; Tessaro, Davide Advanced Synthesis and Catalysis, 2007 , vol. 349, # 8-9 p. 1345 - 1348

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.337
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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