Z-D-Phg-OH

Name: Z-D-Phg-OH
Brand: ChemScene
Availability: InStock
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CAS No. 17609-52-8
Cat. No. CS-0005785
Purity≥97%
MDL No.MFCD00064977

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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General Information

CAS No. 17609-52-8
Cat. No. CS-0005785
Purity ≥97%
MDL No. MFCD00064977
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₆H₁₅NO₄
Molecular Weight 285.29
Synonym(s) D-Cbz phenylglycine
SMILES O=C(N[C@@H](C(O)=O)C1=CC=CC=C1)OCC2=CC=CC=C2

Description

Z-D-Phg-OH is a bench-stable, moisture-tolerant dipeptide building block featuring a D-phenylglycine residue protected with a Z (benzyloxycarbonyl) group. This configuration enables efficient incorporation into peptide sequences under standard coupling conditions, offering reliable stereochemical control and compatibility with diverse synthetic workflows in peptide chemistry.

Application

Z-D-Phg-OH serves as a key chiral building block in peptide synthesis, enabling efficient access to D-phenylglycine-containing sequences. Its Z (benzyloxycarbonyl) protection ensures stability during coupling steps, while the hydroxyl group provides a handle for orthogonal derivatization. The compound exhibits excellent functional group tolerance and facilitates high-yielding, stereospecific couplings in standard solid-phase and solution-phase protocols.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

TPSA 75.63
LogP 2.7387
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 5

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Glycine and derivatives

Life Science Amino Acids and their Derivatives N-protected amino acid

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Unnatural Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Z-D-Phg-OH

CAS No. 17609-52-8

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