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CS-W001157 4
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(R)-2-(((Benzyloxy)carbonyl)amino)butanoic acid

  • CAS No. 2900-20-1

  • Cat. No. CS-0041677
  • Molecule weight237.25
  • Purity≥97%
  • MDL No.MFCD00136772

*For research and further manufacturing use only, not for direct human use.

(R)-2-(((Benzyloxy)carbonyl)amino)butanoic acid|CS-0041677

Structure of 2900-20-1

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General Information

  • CAS No. 2900-20-1
  • Cat. No. CS-0041677
  • Purity ≥97%
  • MDL No. MFCD00136772
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₅NO₄
  • Molecular Weight 237.25
  • Synonym(s) N-(Benzyloxycarbonyl)-D-2-aminobutanoic acid
  • SMILES CC[C@@H](NC(OCC1=CC=CC=C1)=O)C(O)=O

Description

(R)-2-(((Benzyloxy)carbonyl)amino)butanoic acid is a chiral amino acid derivative featuring a benzyl ester-protected side chain. This configuration enables selective incorporation into peptide sequences during solid-phase synthesis, offering enhanced stability and controlled deprotection under mild conditions. The benzyloxy carbonyl group facilitates efficient coupling while minimizing racemization.

Application

(R)-2-(((Benzyloxy)carbonyl)amino)butanoic acid serves as a stable, bench-ready chiral building block for peptide synthesis and medicinal chemistry. Its (R)-configuration provides stereochemical control in the construction of bioactive peptides, while the benzyloxycarbonyl (Cbz) group offers orthogonal protection compatible with standard deprotection protocols. The molecule exhibits excellent functional group tolerance and facilitates efficient coupling reactions, enabling reliable access to complex scaffolds in both academic and industrial settings.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   1.776
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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