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CS-W001157 4
Total: USD 88.00

D(-)-2-Aminobutyric acid

  • CAS No. 2623-91-8

  • Cat. No. CS-D1130
  • Purity≥97%
  • MDL No.MFCD00064414

*For research and further manufacturing use only, not for direct human use.

D(-)-2-Aminobutyric acid|CS-D1130

Structure of 2623-91-8

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General Information

  • CAS No. 2623-91-8
  • Cat. No. CS-D1130
  • Purity ≥97%
  • MDL No. MFCD00064414
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉NO₂
  • Molecular Weight 103.12
  • Synonym(s) None
  • SMILES CC[C@@H](N)C(O)=O

Description

D(-)-2-Aminobutyric acid is a stereochemically defined, bench-stable amino acid featuring a chiral center at the 2-position. This configuration imparts distinct conformational properties valuable in peptide synthesis and structural studies. The molecule integrates readily into peptidomimetic architectures, offering enhanced metabolic stability and controlled bioavailability in biochemical applications.

Application

D(-)-2-Aminobutyric acid serves as a valuable chiral building block in peptide synthesis and medicinal chemistry, offering well-established stereochemical control. Its stability under standard reaction conditions and compatibility with common coupling protocols enable efficient incorporation into bioactive scaffolds. Functions as a key structural motif in the development of peptidomimetics and enzyme inhibitors.

Synthesis

  • Route1

    References

    • Compagnone, Reinaldo S.; Rapoport, Henry Journal of Organic Chemistry, 1986 , vol. 51, # 10 p. 1713 - 1719
  • Route2
    • null|null
      600728-78-7
    • ~76%
    • In-stock
      D(-)-2-Aminobutyric acid|CS-D1130
      2623-91-8

    References

    • Badorrey, Ramon; Cativiela, Carlos; Diaz-de-Villegas, Maria D.; Diez, Roberto; Galvez, Jose A. European Journal of Organic Chemistry, 2003 , # 12 p. 2268 - 2275
  • Route3
    • H-Abu-OH Levetiracetam Impurity|CS-0213953
      1492-24-6
    • ~%
    • In-stock
      D(-)-2-Aminobutyric acid|CS-D1130
      2623-91-8

    References

    • BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2006/18182 A1, 2006 ; Location in patent: Page/Page column 63 ; WO 2006/018182 A1 Title/Abstract Full Text Show Details BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2006/18185 A2, 2006 ; Location in patent: Page/Page column 63 ; WO 2006/018185 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   -0.1917
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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