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CS-W001157 4
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Hydroxy-PEG1-CH2-Boc

  • CAS No. 287174-32-7

  • Cat. No. CS-0115009
  • Purity≥95%
  • MDL No.MFCD27635155

*For research and further manufacturing use only, not for direct human use.

Hydroxy-PEG1-CH2-Boc|CS-0115009

Structure of 287174-32-7

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General Information

  • CAS No. 287174-32-7
  • Cat. No. CS-0115009
  • Purity ≥95%
  • MDL No. MFCD27635155
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆O₄
  • Molecular Weight 176.21
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)COCCO

Description

Hydroxy-PEG1-CH2-Boc features a hydroxyl-terminated PEG chain linked to a Boc-protected amine via a methylene spacer. This bifunctional construct enables selective conjugation and protection strategies in peptide synthesis and bioconjugation workflows. The hydrophilic PEG segment enhances solubility, while the stable Boc group facilitates controlled deprotection under mild acidic conditions.

Application

Hydroxy-PEG1-CH2-Boc serves as a versatile, bench-stable building block for the synthesis of PEGylated compounds and bioconjugates. The hydroxyl group enables straightforward derivatization, while the Boc-protected amine offers orthogonal functionality for sequential coupling strategies. Its PEG1 spacer provides enhanced solubility and reduced aggregation in aqueous environments, facilitating purification and downstream applications in drug delivery and peptide chemistry.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   55.76
  • LogP   0.337
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   4

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