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CS-W001157 4
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5-Methoxy-4-methyl-2,3-dihydro-1H-inden-1-one

  • CAS No. 28596-58-9

  • Cat. No. CS-0201413
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Methoxy-4-methyl-2,3-dihydro-1H-inden-1-one|CS-0201413

Structure of 28596-58-9

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General Information

  • CAS No. 28596-58-9
  • Cat. No. CS-0201413
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂O₂
  • Molecular Weight 176.21
  • Synonym(s) 5-methoxy-4-methyl-1-indanone
  • SMILES O=C1CCC2=C1C=CC(OC)=C2C

Description

This indenone derivative features a methoxy group at the 5-position and a methyl substituent at the 4-position, enhancing solubility and electronic modulation. The dihydroindene core provides a rigid, electron-rich scaffold ideal for synthetic intermediates in pharmaceutical and agrochemical development under standard conditions.

Application

5-Methoxy-4-methyl-2,3-dihydro-1H-inden-1-one serves as a versatile intermediate in the synthesis of bioactive heterocycles and pharmaceutical scaffolds. Its fused bicyclic structure offers defined stereochemistry and predictable reactivity, enabling selective functionalization at the carbonyl and olefinic sites. The methoxy and methyl substituents provide favorable electronic tuning and enhanced bench stability, facilitating straightforward purification and integration into multistep synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.13252
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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