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Structure of 28485-17-8
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Ethyl 4-hydroxy-2-oxo-1,2-dihydropyrimidine-5-carboxylate serves as a key heterocyclic scaffold in medicinal chemistry, featuring a hydroxyl group at C4 and a carbonyl at C2 that enable diverse functionalization. This bench-stable intermediate integrates readily into synthetic sequences for pyrimidine-based bioactive compounds.
Ethyl 4-hydroxy-2-oxo-1,2-dihydropyrimidine-5-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyrimidine-based scaffolds. The molecule features orthogonal functional groups—carboxylate ester and enolizable C4 hydroxyl—that facilitate sequential transformations. It participates reliably in nucleophilic additions, condensations, and cyclizations under mild conditions, with demonstrated stability for bench storage and straightforward purification. Widely used in medicinal chemistry and agrochemical research, it functions as a key intermediate in the construction of bioactive pyrimidines.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: