3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-fluorophenyl)propanoic acid

Name: 3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-fluorophenyl)propanoic acid
Brand: ChemScene
Availability: InStock
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CAS No. 284492-07-5
Cat. No. CS-0181510
Purity≥98%
MDL No.MFCD01863214

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3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-fluorophenyl)propanoic acid|CS-0181510

Structure of 284492-07-5

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Description

This fluorenylmethoxy carbamate-protected amino acid derivative features a sterically hindered, electron-deficient aryl moiety that enhances stability and facilitates efficient coupling in peptide synthesis. The 3-fluorophenyl group imparts favorable solubility and reduces aggregation during chain elongation.

Application

3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-fluorophenyl)propanoic acid serves as a robust amino acid derivative for peptide synthesis, offering enhanced solubility and stability during coupling steps. The fluorenylmethoxycarbonyl (Fmoc) group enables efficient deprotection under mild basic conditions, while the 3-fluorophenyl moiety provides steric and electronic modulation for synthetic diversification. This compound facilitates reliable N-terminal protection in solid-phase and solution-phase workflows.

General Information

CAS No. 284492-07-5
Cat. No. CS-0181510
Purity ≥98%
MDL No. MFCD01863214
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₄H₂₀FNO₄
Molecular Weight 405.42
Synonym(s) 3-N-FMOC-3-(3-FLUOROPHENYL)PROPIONIC ACID
SMILES O=C(O)CC(NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C4=CC=CC(F)=C4

Computational Chemistry Data

TPSA 75.63
LogP 4.8802
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 6

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Fluoride

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-fluorophenyl)propanoic acid

CAS No. 284492-07-5

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