Fmoc-(RS)-3-amino-3-(3-pyridyl)-propionic acid

Name: Fmoc-(RS)-3-amino-3-(3-pyridyl)-propionic acid
Brand: ChemScene
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CAS No. 284491-95-8
Cat. No. CS-0182703
Purity≥96%
MDL No.None

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FedEx Limited Quantities Ground	$0.00
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Fmoc-(RS)-3-amino-3-(3-pyridyl)-propionic acid|CS-0182703

Structure of 284491-95-8

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General Information

CAS No. 284491-95-8
Cat. No. CS-0182703
Purity ≥96%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₃H₂₀N₂O₄
Molecular Weight 388.42
Synonym(s) 3-(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-pyridin-3-ylpropanoic acid
SMILES O=C(CC(C1=CC=CN=C1)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O)O

Description

Fmoc-(RS)-3-amino-3-(3-pyridyl)-propionic acid is a chiral building block featuring a pyridyl group at the β-position, enabling site-specific conjugation in peptide synthesis. The Fmoc group ensures efficient orthogonal protection, while the aromatic pyridyl moiety enhances solubility and facilitates downstream functionalization. This derivative integrates readily into peptidomimetics and bioactive sequences under standard coupling conditions.

Application

Fmoc-(RS)-3-amino-3-(3-pyridyl)-propionic acid serves as a versatile building block for peptide synthesis, enabling the incorporation of a pyridyl-containing side chain with enhanced solubility and orthogonal functionality. The Fmoc group facilitates efficient deprotection under mild basic conditions, while the 3-pyridyl moiety provides a handle for metal coordination or further derivatization. Its bench-stable nature and compatibility with standard coupling protocols make it ideal for solid-phase peptide synthesis and the construction of bioactive heterocyclic scaffolds.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

TPSA 88.52
LogP 4.1361
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 6

Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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Fmoc-(RS)-3-amino-3-(3-pyridyl)-propionic acid

CAS No. 284491-95-8

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