(S)-5-Carbamoyl-3-(9H-fluoren-9-ylmethoxycarbonyl-amino)-pentanoic acid

Name: (S)-5-Carbamoyl-3-(9H-fluoren-9-ylmethoxycarbonyl-amino)-pentanoic acid
Brand: ChemScene
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CAS No. 283160-17-8
Cat. No. CS-0149948
Purity≥95%
MDL No.MFCD01862847

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(S)-5-Carbamoyl-3-(9H-fluoren-9-ylmethoxycarbonyl-amino)-pentanoic acid|CS-0149948

Structure of 283160-17-8

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General Information

CAS No. 283160-17-8
Cat. No. CS-0149948
Purity ≥95%
MDL No. MFCD01862847
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₁H₂₂N₂O₅
Molecular Weight 382.41
Synonym(s) (S)-3-(FMOC-AMINO)ADIPIC ACID 6-AMIDE
SMILES NC(CC[C@@H](CC(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=O

Description

This chiral building block features a protected amino acid scaffold with orthogonal functionality, enabling seamless integration into peptide synthesis workflows. The fluoren-9-ylmethoxycarbonyl (Fmoc) group ensures efficient, base-labile protection, while the carbamoyl moiety provides a polar handle for downstream conjugation. Bench-stable and moisture-tolerant, it supports high-yielding coupling reactions under standard conditions.

Application

(S)-5-Carbamoyl-3-(9H-fluoren-9-ylmethoxycarbonyl-amino)-pentanoic acid serves as a versatile chiral building block for peptide and peptidomimetic synthesis, offering orthogonal protection via the Fmoc group and a carbamoyl handle for downstream functionalization. Its bench-stable structure facilitates straightforward purification and compatibility with standard coupling protocols, enabling efficient access to complex scaffolds in medicinal chemistry workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

TPSA 118.72
LogP 2.6339
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 8

Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Functional Group Amide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-5-Carbamoyl-3-(9H-fluoren-9-ylmethoxycarbonyl-amino)-pentanoic acid

CAS No. 283160-17-8

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