Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(4-Bromobenzylidene)malononitrile

  • CAS No. 2826-24-6

  • Cat. No. CS-0110446
  • Purity≥97%
  • MDL No.MFCD00176213

*For research and further manufacturing use only, not for direct human use.

2-(4-Bromobenzylidene)malononitrile|CS-0110446

Structure of 2826-24-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 2826-24-6
  • Cat. No. CS-0110446
  • Purity ≥97%
  • MDL No. MFCD00176213
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₅BrN₂
  • Molecular Weight 233.07
  • Synonym(s) 2-[(4-Bromophenyl)methylene]malononitrile
  • SMILES N#C/C(C#N)=C/C1=CC=C(C=C1)Br

Description

This malononitrile derivative features a 4-bromobenzylidene group that confers enhanced electron-withdrawing character and facilitates efficient coupling in cross-coupling reactions. The conjugated system enables use in synthesizing functionalized heterocycles and advanced organic materials under standard conditions.

Application

2-(4-Bromobenzylidene)malononitrile serves as a versatile building block in heterocyclic synthesis, enabling efficient access to fused pyrimidine and quinoline scaffolds via Knoevenagel condensation and subsequent cyclization. Its bromo-substituted aryl group facilitates downstream palladium-catalyzed cross-coupling reactions, while the dual nitrile groups provide high reactivity in nucleophilic addition and cycloaddition processes. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it well-suited for scalable medicinal chemistry campaigns and process development.

Synthesis

  • Route1
    • In-stock
      4-Bromobenzaldehyde|CS-W001138
      1122-91-4
    • null|null
      109-77-3
    • ~99%
    • In-stock
      2-(4-Bromobenzylidene)malononitrile|CS-0110446
      2826-24-6

    References

    • Wiles, Charlotte; Watts, Paul; Haswell, Stephen J. Tetrahedron, 2004 , vol. 60, # 38 p. 8421 - 8427
  • Route2
    • N-(4-Bromobenzylidene)-4-methylbenzenesulfonamide|CS-1634962
      36176-90-6
    • null|null
      109-77-3
    • ~95%
    • In-stock
      2-(4-Bromobenzylidene)malononitrile|CS-0110446
      2826-24-6

    References

    • Chiba, Ryoichi; Oriyama, Takeshi Chemistry Letters, 2008 , vol. 37, # 12 p. 1218 - 1219

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   47.58
  • LogP   2.87966
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-(4-Bromobenzylidene)malononitrile sigma2-(4-Bromobenzylidene)malononitrile manufacturer2-(4-Bromobenzylidene)malononitrile price2-(4-Bromobenzylidene)malononitrile structure2-(4-Bromobenzylidene)malononitrile SDSbuy 2-(4-Bromobenzylidene)malononitrile2-(4-Bromobenzylidene)malononitrile supplier2-(4-Bromobenzylidene)malononitrile uses2-(4-Bromobenzylidene)malononitrile molecular weightprice of 2-(4-Bromobenzylidene)malononitrile2-(4-Bromobenzylidene)malononitrile chemical name formula of 2-(4-Bromobenzylidene)malononitrile
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label