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Structure of 280773-17-3
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This pyridine-linked amide integrates a 5-chloro-2-pyridinyl group with a methoxy-substituted benzamide scaffold, delivering enhanced solubility and metabolic stability. The amino functionality enables direct conjugation in bioconjugation workflows, while the electron-deficient pyridine ring facilitates targeted interactions in kinase inhibitor design.
2-Amino-N-(5-chloro-2-pyridinyl)-5-methoxybenzamide serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard amide coupling and Suzuki-Miyaura cross-coupling reactions. Its ortho-amino and methoxy functionalities offer complementary sites for functionalization, while the 5-chloropyridine moiety facilitates further diversification via palladium-catalyzed transformations. The compound exhibits good bench stability and is readily purified by chromatography, supporting its use in multi-step synthetic sequences targeting kinase inhibitors and other pharmaceutical scaffolds.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: