(R)-1-(Pyridin-2-yl)ethanol

Name: (R)-1-(Pyridin-2-yl)ethanol
Brand: ChemScene
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CAS No. 27911-63-3
Cat. No. CS-0040476
Purity≥95%
MDL No.MFCD04972322

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 27911-63-3
Cat. No. CS-0040476
Purity ≥95%
MDL No. MFCD04972322
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₉NO
Molecular Weight 123.15
Synonym(s) (R)-α-Methyl-2-pyridinemethanol
SMILES O[C@H](C)C1=NC=CC=C1

Description

(R)-1-(Pyridin-2-yl)ethanol is a chiral alcohol featuring a pyridine ring directly linked to a stereodefined hydroxymethyl group. This configuration enables selective incorporation into asymmetric synthesis, where the pyridyl moiety serves as a directing group or ligand anchor. The compound exhibits favorable solubility in common organic solvents and stability under standard bench conditions.

Application

(R)-1-(Pyridin-2-yl)ethanol serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of stereoselective pharmaceutical intermediates. Its pyridyl alcohol functionality supports diverse transformations, including oxidation, etherification, and coupling reactions. The compound exhibits good bench stability, facilitates straightforward purification, and functions effectively in asymmetric synthesis workflows requiring controlled stereochemistry.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 33.12
LogP 1.1349
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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(R)-1-(Pyridin-2-yl)ethanol

CAS No. 27911-63-3

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