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Structure of 27582-14-5
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4-Amino-2-methyl-3-nitropyridine features a pyridine core functionalized with electron-donating amino and methyl groups at positions 4 and 2, respectively, paired with a strongly electron-withdrawing nitro group at position 3. This arrangement creates a polar, resonance-stabilized system ideal for nucleophilic substitution and transition-metal-catalyzed coupling reactions. The compound exhibits bench-stable handling under standard conditions and integrates readily into complex heterocyclic scaffolds.
4-Amino-2-methyl-3-nitropyridine serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted pyridine scaffolds through sequential functionalization. The amino and nitro groups exhibit orthogonal reactivity, facilitating selective transformations such as reduction, coupling, or electrophilic substitution. Its bench-stable nature and compatibility with common reaction conditions make it suitable for iterative synthesis workflows in medicinal chemistry and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: