4-Bromo-5-chlorobenzene-1,2-diamine

Name: 4-Bromo-5-chlorobenzene-1,2-diamine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 75293-95-7
Cat. No. CS-0179339
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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4-Bromo-5-chlorobenzene-1,2-diamine|CS-0179339

Structure of 75293-95-7

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Description

4-Bromo-5-chlorobenzene-1,2-diamine offers a dual halogenated aromatic scaffold with strategically positioned amino groups, enabling precise coupling in heterocyclic synthesis. This electron-deficient diamine integrates readily into advanced pharmaceutical intermediates and functional materials, providing high reactivity under standard conditions.

Application

4-Bromo-5-chlorobenzene-1,2-diamine serves as a versatile building block in medicinal chemistry and materials science, enabling the construction of heterocyclic scaffolds via cyclization or cross-coupling reactions. Its dual halogenated aryl functionality offers orthogonal reactivity for Pd-catalyzed transformations, while the diamine moiety provides sites for derivatization or coordination in catalytic systems. Bench-stable and readily purified by recrystallization, it functions effectively in standard synthetic workflows requiring functional group tolerance and predictable regiochemistry.

General Information

CAS No. 75293-95-7
Cat. No. CS-0179339
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₆BrClN₂
Molecular Weight 221.48
Synonym(s) 4-BROMO-5-CHLORO-BENZENE-1,2-DIAMINE
SMILES NC1=CC(Cl)=C(Br)C=C1N

Computational Chemistry Data

TPSA 52.04
LogP 2.2669
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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4-Bromo-5-chlorobenzene-1,2-diamine

CAS No. 75293-95-7

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