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Structure of 275386-60-2
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This boronate moiety integrates a trimethylsilyl-protected alkyne with a pendant hydroxyl group, enabling orthogonal functionalization in complex synthesis. The silyl-protected alkyne resists moisture and air, while the benzylic alcohol facilitates downstream derivatization under mild conditions.
(4-((Trimethylsilyl)ethynyl)phenyl)methanol serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted phenylacetylenes via mild desilylation. The trimethylsilyl group provides excellent stability and compatibility with diverse reaction conditions, while the terminal alkyne functionality facilitates copper-catalyzed coupling reactions. Its benzylic alcohol moiety allows for selective derivatization or protection, supporting orthogonal functionalization strategies. This compound is particularly valuable in constructing complex scaffolds for medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: