(R)-2-((tert-Butoxycarbonyl)amino)-2-(4-hydroxyphenyl)acetic acid

Name: (R)-2-((tert-Butoxycarbonyl)amino)-2-(4-hydroxyphenyl)acetic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 27460-85-1
Cat. No. CS-0197100
Purity≥97%
MDL No.MFCD01861312

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(R)-2-((tert-Butoxycarbonyl)amino)-2-(4-hydroxyphenyl)acetic acid|CS-0197100

Structure of 27460-85-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 27460-85-1
Cat. No. CS-0197100
Purity ≥97%
MDL No. MFCD01861312
Storage RT, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₇NO₅
Molecular Weight 267.28
Synonym(s) Boc-4-hydroxy-D-phenylglycine
SMILES CC(C)(OC(N[C@@H](C(O)=O)C1=CC=C(O)C=C1)=O)C

Description

(R)-2-((tert-Butoxycarbonyl)amino)-2-(4-hydroxyphenyl)acetic acid is a chiral building block featuring a protected amino group and a phenolic hydroxyl, enabling selective functionalization in peptide and pharmaceutical synthesis. This bench-stable derivative integrates readily into complex molecular architectures under standard conditions.

Application

(R)-2-((tert-Butoxycarbonyl)amino)-2-(4-hydroxyphenyl)acetic acid serves as a key chiral building block for peptide and peptidomimetic synthesis, offering high stereoselectivity and bench stability. The Boc-protected amine enables straightforward deprotection under mild acidic conditions, while the phenolic hydroxyl group supports orthogonal functionalization. Its well-defined reactivity facilitates incorporation into complex scaffolds relevant to medicinal chemistry and API development.

Synthesis

Route1
- In-stock
  
  24424-99-5
- In-stock
  
  22818-40-2
- ~99%
- In-stock
  
  27460-85-1
References
- Ohta, Yosuke; Terada, Kayo; Masuda, Toshio; Sanda, Fumio Heterocycles, 2009 , vol. 78, # 10 p. 2523 - 2530

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 95.86
LogP 2.0426
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 3

Other Classifications

Building Blocks Functional Group Boc

Building Blocks Functional Group Phenol

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

27460-85-1 sigma27460-85-1 manufacturer27460-85-1 price27460-85-1 structure27460-85-1 SDSbuy 27460-85-127460-85-1 supplier27460-85-1 uses27460-85-1 molecular weightprice of 27460-85-127460-85-1 chemical name formula of 27460-85-1

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(R)-2-((tert-Butoxycarbonyl)amino)-2-(4-hydroxyphenyl)acetic acid

CAS No. 27460-85-1

Recommended Products