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CS-W001157 4
Total: USD 88.00

4-Bromo-3-(hydroxymethyl)phenol

  • CAS No. 2737-20-4

  • Cat. No. CS-0158884
  • Purity≥97%
  • MDL No.MFCD13178305

*For research and further manufacturing use only, not for direct human use.

4-Bromo-3-(hydroxymethyl)phenol|CS-0158884

Structure of 2737-20-4

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General Information

  • CAS No. 2737-20-4
  • Cat. No. CS-0158884
  • Purity ≥97%
  • MDL No. MFCD13178305
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇BrO₂
  • Molecular Weight 203.03
  • Synonym(s) Crisaborole-012
  • SMILES OCC1=CC(O)=CC=C1Br

Description

4-Bromo-3-(hydroxymethyl)phenol features a phenolic hydroxyl group flanked by a bromine substituent and a reactive hydroxymethyl handle. This combination enables direct functionalization in synthetic sequences, particularly in cross-coupling or derivatization reactions. The molecule exhibits bench-stable handling characteristics and compatibility with standard organic synthesis protocols.

Application

4-Bromo-3-(hydroxymethyl)phenol serves as a versatile building block in medicinal chemistry and materials synthesis, enabling efficient access to functionalized aromatic scaffolds. The bromo group facilitates palladium-catalyzed cross-coupling reactions, while the hydroxymethyl functionality offers a handle for oxidation, protection, or derivatization. Its bench-stable nature and compatibility with standard purification methods support reliable integration into multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.647
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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