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CS-W001157 4
Total: USD 88.00

3-Methylene-8-Boc-8-azabicyclo[3.2.1]octane

  • CAS No. 273207-57-1

  • Cat. No. CS-0037643
  • Molecule weight223.31
  • Purity≥98%
  • MDL No.MFCD22381986

*For research and further manufacturing use only, not for direct human use.

3-Methylene-8-Boc-8-azabicyclo[3.2.1]octane|CS-0037643

Structure of 273207-57-1

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General Information

  • CAS No. 273207-57-1
  • Cat. No. CS-0037643
  • Purity ≥98%
  • MDL No. MFCD22381986
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₁NO₂
  • Molecular Weight 223.31
  • Synonym(s) tert-butyl 3-methylidene-8-azabicyclo[3.2.1]octane-8-carboxylate
  • SMILES C=C1CC2CCC(N2C(OC(C)(C)C)=O)C1

Synthesis

  • Route1
    • null|null
      1779-49-3
    • In-stock
      N-Boc-nortropinone|CS-W001484
      185099-67-6
    • ~89%
    • In-stock
      3-Methylene-8-Boc-8-azabicyclo[3.2.1]octane|CS-0037643
      273207-57-1

    References

    • EXELIXIS, INC.; RICE, Kenneth Patent: WO2012/71509 A2, 2012 ; Location in patent: Page/Page column 160 ; WO 2012/071509 A2
  • Route2

    References

    • AVENTIS PHARMACEUTICALS INC. Patent: WO2004/100946 A1, 2004 ; Location in patent: Page 59 ; WO 2004/100946 A1
  • Route3

    References

    • Pfizer Inc. Patent: US6194438 B1, 2001 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   3.1045
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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