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Structure of 26893-68-5
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6-Nitropyridine-2-carboxylic acid features a pyridine ring bearing both a nitro group at the 6-position and a carboxylic acid at the 2-position, creating a dual functionalized scaffold with strong electron-withdrawing character. This arrangement enhances its utility in metal coordination, pharmaceutical intermediates, and as a building block for heterocyclic systems requiring precise electronic tuning.
6-Nitropyridine-2-carboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling direct functionalization at both the pyridine nitrogen and carboxylic acid terminus. Its dual functionality facilitates amide coupling, nucleophilic substitution, and metal-catalyzed cross-coupling reactions under standard conditions. The nitro group enhances electrophilicity for further derivatization, while the carboxylic acid provides a handle for conjugation or salt formation. Bench-stable and readily purified by recrystallization, it supports scalable synthesis of complex nitrogen-containing scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: