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CS-W001157 4
Total: USD 88.00

(1-Methyl-1H-indazol-5-yl)methanamine

  • CAS No. 267413-27-4

  • Cat. No. CS-0054515
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1-Methyl-1H-indazol-5-yl)methanamine|CS-0054515

Structure of 267413-27-4

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General Information

  • CAS No. 267413-27-4
  • Cat. No. CS-0054515
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁N₃
  • Molecular Weight 161.20
  • Synonym(s) 5-(Aminomethyl)-1-methyl-1H-indazole
  • SMILES NCC1=CC2=C(N(C)N=C2)C=C1

Description

This bench-stable amine features a 1-methyl-1H-indazol-5-yl scaffold that delivers enhanced solubility and metabolic stability. The pendant primary amine enables straightforward functionalization, facilitating integration into diverse bioactive scaffolds. Its electron-rich heterocycle supports efficient coupling reactions under standard conditions, making it ideal for medicinal chemistry applications.

Application

(1-Methyl-1H-indazol-5-yl)methanamine serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, enabling efficient access to indazole-based pharmacophores. Its primary amine functionality facilitates straightforward derivatization via alkylation, acylation, or coupling reactions, while the electron-rich indazole core supports further functionalization. The compound exhibits good bench stability and compatibility with standard purification methods, making it well-suited for iterative synthesis campaigns in drug discovery.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   43.84
  • LogP   1.032
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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