Fmoc-β-HoMet-OH

Name: Fmoc-β-HoMet-OH
Brand: ChemScene
Availability: InStock
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CAS No. 266359-48-2
Cat. No. CS-W011748
Purity≥98%
MDL No.MFCD01862844

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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*For research and further manufacturing use only, not for direct human use.

Structure of 266359-48-2

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Description

Fmoc-β-HoMet-OH is a specialized amino acid derivative featuring a β-homologated methionine scaffold with a fluorenylmethoxy carbonyl (Fmoc) protecting group. This configuration enables direct incorporation into peptide chains via standard solid-phase synthesis protocols, offering enhanced stability and controlled reactivity. The Fmoc moiety facilitates efficient deprotection under mild basic conditions, streamlining sequence assembly in complex peptide architectures.

Application

Fmoc-β-HoMet-OH serves as a key building block for the synthesis of peptide-based therapeutics, enabling site-specific incorporation of β-homolanthionine residues. Its Fmoc group provides orthogonal protection for amine functionality, while the thiol side chain facilitates disulfide bond formation or bioconjugation strategies. The compound exhibits excellent bench stability and compatibility with standard solid-phase peptide synthesis protocols, supporting efficient coupling and purification workflows.

General Information

CAS No. 266359-48-2
Cat. No. CS-W011748
Purity ≥98%
MDL No. MFCD01862844
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₁H₂₃NO₄S
Molecular Weight 385.48
Synonym(s) None
SMILES CSCC[C@H](NC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)CC(O)=O

Computational Chemistry Data

TPSA 75.63
LogP 4.1215
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 8

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Building Blocks Functional Group Fmoc

Life Science Amino Acids and their Derivatives Methionine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

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Fmoc-β-HoMet-OH

CAS No. 266359-48-2

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