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CS-W001157 4
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2-Methoxy-3-methylbenzoic acid

  • CAS No. 26507-91-5

  • Cat. No. CS-0131363
  • Molecule weight166.17
  • Purity≥98%
  • MDL No.MFCD00016522

*For research and further manufacturing use only, not for direct human use.

2-Methoxy-3-methylbenzoic acid|CS-0131363

Structure of 26507-91-5

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General Information

  • CAS No. 26507-91-5
  • Cat. No. CS-0131363
  • Purity ≥98%
  • MDL No. MFCD00016522
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₃
  • Molecular Weight 166.17
  • Synonym(s) Methoxyl-m-toluic acid
  • SMILES O=C(O)C1=CC=CC(C)=C1OC

Description

2-Methoxy-3-methylbenzoic acid features a strategically positioned methoxy group and methyl substituent that modulate electronic distribution and steric profile. This combination enhances solubility in organic solvents while maintaining stability under standard bench conditions, facilitating straightforward integration into synthetic sequences involving esterification, amidation, or coupling reactions.

Application

2-Methoxy-3-methylbenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, offering a well-defined ortho-substituted aromatic scaffold. Its carboxylic acid functionality enables direct coupling reactions (e.g., amidation, esterification), while the methoxy and methyl groups provide predictable steric and electronic modulation. The compound exhibits good bench stability and facilitates efficient purification via recrystallization or chromatography, supporting its use in multi-step syntheses of bioactive molecules.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.70182
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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