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CS-W001157 4
Total: USD 88.00

Pyrimidin-5-ol

  • CAS No. 26456-59-7

  • Cat. No. CS-W019717
  • Purity≥98%
  • MDL No.MFCD06412562

*For research and further manufacturing use only, not for direct human use.

Pyrimidin-5-ol|CS-W019717

Structure of 26456-59-7

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General Information

  • CAS No. 26456-59-7
  • Cat. No. CS-W019717
  • Purity ≥98%
  • MDL No. MFCD06412562
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄N₂O
  • Molecular Weight 96.09
  • Synonym(s) 5-Hydroxypyrimidine
  • SMILES OC1=CN=CN=C1

Description

Pyrimidin-5-ol delivers a robust heterocyclic scaffold with enhanced solubility and stability under standard conditions. This electron-rich pyrimidine derivative features a hydroxyl group at the 5-position, enabling direct functionalization and integration into bioactive molecules. The compound serves as a key intermediate in medicinal chemistry, particularly for kinase inhibitors and nucleoside analogs.

Application

Pyrimidin-5-ol serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to pyrimidine-based scaffolds. Its hydroxyl group facilitates direct functionalization or metal-catalyzed coupling reactions, while the core ring exhibits good bench stability and compatibility with common protecting groups. This compound functions effectively in the synthesis of nucleoside analogs and kinase inhibitors, offering predictable reactivity in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.01
  • LogP   0.1822
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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