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Mc-Gly-Gly-Phe-Gly-PAB-OH

  • CAS No. 2632342-05-1

  • Cat. No. CS-0129401
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Mc-Gly-Gly-Phe-Gly-PAB-OH|CS-0129401

Structure of 2632342-05-1

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General Information

  • CAS No. 2632342-05-1
  • Cat. No. CS-0129401
  • Purity ≥97%
  • MDL No. None
  • Storage polypeptide, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₂H₃₈N₆O₈
  • Molecular Weight 634.68
  • Synonym(s) Mc-GGFG-PAB-OH
  • SMILES OCC(C=C1)=CC=C1NC(CNC([C@H](CC2=CC=CC=C2)NC(CNC(CNC(CCCCCN3C(C=CC3=O)=O)=O)=O)=O)=O)=O

Description

Mc-Gly-Gly-Phe-Gly-PAB-OH features a hydrophilic tetrapeptide core flanked by a C-terminal PAB-OH handle, enabling efficient conjugation in bioorthogonal labeling workflows. This sequence combines enhanced solubility with robust stability under physiological conditions, facilitating use in peptide-protein coupling and targeted delivery applications.

Application

Mc-Gly-Gly-Phe-Gly-PAB-OH serves as a stable, bench-ready peptide-based building block for the synthesis of bioactive conjugates and peptidomimetic scaffolds. Its orthogonal PAB (para-aminobenzoyl) handle enables efficient site-specific attachment to solid supports or reporter molecules, while the tetrapeptide core provides structural rigidity and proteolytic resistance. The sequence exhibits excellent solubility and purification compatibility in standard HPLC workflows, facilitating scalable integration into modular synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   203.11
  • LogP   -0.3211
  • H_Acceptors   8
  • H_Donors   6
  • Rotatable_Bonds   18

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