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N1-(2-Methylnaphthalen-1-yl)-N2-(pyridin-2-ylmethyl)oxalamide

  • CAS No. 2611225-93-3

  • Cat. No. CS-0530594
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N1-(2-Methylnaphthalen-1-yl)-N2-(pyridin-2-ylmethyl)oxalamide|CS-0530594

Structure of 2611225-93-3

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General Information

  • CAS No. 2611225-93-3
  • Cat. No. CS-0530594
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₁₇N₃O₂
  • Molecular Weight None
  • Synonym(s) None
  • SMILES O=C(NC1=C2C=CC=CC2=CC=C1C)C(NCC3=NC=CC=C3)=O

Description

This oxalamide features a 2-methylnaphthalen-1-yl group linked to a pyridin-2-ylmethyl moiety via a rigid amide backbone, enabling strong π-stacking and directional binding. The electron-rich naphthalene unit enhances aromatic interactions, while the pyridine nitrogen offers coordination potential. Bench-stable and moisture-tolerant, it serves as a modular scaffold for supramolecular systems and functional materials.

Application

N1-(2-Methylnaphthalen-1-yl)-N2-(pyridin-2-ylmethyl)oxalamide serves as a versatile bifunctional building block in medicinal chemistry, enabling the construction of constrained heterocyclic scaffolds. Its oxalamide core provides robust hydrogen-bonding capacity and structural rigidity, while the 2-methylnaphthalene and pyridin-2-ylmethyl moieties offer orthogonal functional handles for further derivatization. The compound exhibits good bench stability, facilitates efficient purification, and supports diverse coupling reactions under standard conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07,GHS08,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H372-H411
Precautionary Statements : P260-P264-P270-P273-P330-P391-P501

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Computational Chemistry Data

  • TPSA   71.09
  • LogP   2.79812
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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