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N1-(Furan-2-ylmethyl)-N2-(2-methylnaphthalen-1-yl)oxalamide

  • CAS No. 2072109-00-1

  • Cat. No. CS-0492446
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N1-(Furan-2-ylmethyl)-N2-(2-methylnaphthalen-1-yl)oxalamide|CS-0492446

Structure of 2072109-00-1

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General Information

  • CAS No. 2072109-00-1
  • Cat. No. CS-0492446
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₁₆N₂O₃
  • Molecular Weight 308.33
  • Synonym(s) None
  • SMILES C1C=C(OC=1)CNC(=O)C(=O)NC2C3C(=CC=CC=3)C=CC=2C

Description

N1-(Furan-2-ylmethyl)-N2-(2-methylnaphthalen-1-yl)oxalamide features a fused heteroaromatic-fused alkylaryl scaffold with dual recognition elements. This oxalamide integrates a furan-based donor moiety and a sterically hindered naphthalene acceptor, enabling precise molecular recognition in supramolecular systems under standard conditions.

Application

N1-(Furan-2-ylmethyl)-N2-(2-methylnaphthalen-1-yl)oxalamide serves as a versatile bifunctional building block in medicinal chemistry, enabling the construction of complex heterocyclic scaffolds via amide coupling and cyclization reactions. The furan-2-ylmethyl moiety provides a polar, electron-rich site for functionalization, while the 2-methylnaphthalen-1-yl group offers steric bulk and lipophilic character beneficial for target engagement. Its stability under standard synthetic conditions and ease of purification facilitate integration into multi-step synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   71.34
  • LogP   2.99612
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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