Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(2-Iodophenyl)ethan-1-ol

  • CAS No. 26059-40-5

  • Cat. No. CS-0045354
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(2-Iodophenyl)ethan-1-ol|CS-0045354

Structure of 26059-40-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 26059-40-5
  • Cat. No. CS-0045354
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉IO
  • Molecular Weight 248.06
  • Synonym(s) 2-(2'-iodophenyl)ethanol
  • SMILES OCCC1=CC=CC=C1I

Description

2-(2-Iodophenyl)ethan-1-ol features a benzene ring bearing both iodine and hydroxymethyl substituents in ortho orientation, enabling direct functionalization in cross-coupling reactions. The pendant alcohol group provides a handle for derivatization, while the iodophenyl moiety offers high reactivity in palladium-catalyzed transformations. This compound serves as a versatile intermediate in synthetic routes to bioactive molecules and advanced materials.

Application

2-(2-Iodophenyl)ethan-1-ol serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient access to biaryl architectures. Its iodide functionality exhibits high reactivity in Suzuki, Stille, and Negishi couplings, while the pendant primary alcohol offers straightforward derivatization options. The compound demonstrates excellent bench stability and is readily purified by flash chromatography, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Willand-Charnley, Rachel; Puffer, Benjamin W.; Dussault, Patrick H. Journal of the American Chemical Society, 2014 , vol. 136, # 16 p. 5821 - 5823
  • Route2

    References

    • MERCK SHARP and DOHME LIMITED Patent: WO2006/21805 A1, 2006 ; Location in patent: Page/Page column 68 ; WO 2006/021805 A1
  • Route3
    • null|null
      292638-84-7
    • ~48%
    • In-stock
      2-(2-Iodophenyl)ethan-1-ol|CS-0045354
      26059-40-5
    • In-stock
      Acetophenone|CS-0015982
      98-86-2

    References

    • Khalilzadeh, Mohammad A.; Hosseini, Abolfazl; Shokrollahzadeh, Mojtaba; Halvagar, Mohammad R.; Ahmadi, Daryoush; Mohannazadeh, Farajollah; Tajbakhsh, Mahmoud Tetrahedron Letters, 2006 , vol. 47, # 21 p. 3525 - 3528

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.826
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-(2-Iodophenyl)ethan-1-ol sigma2-(2-Iodophenyl)ethan-1-ol manufacturer2-(2-Iodophenyl)ethan-1-ol price2-(2-Iodophenyl)ethan-1-ol structure2-(2-Iodophenyl)ethan-1-ol SDSbuy 2-(2-Iodophenyl)ethan-1-ol2-(2-Iodophenyl)ethan-1-ol supplier2-(2-Iodophenyl)ethan-1-ol uses2-(2-Iodophenyl)ethan-1-ol molecular weightprice of 2-(2-Iodophenyl)ethan-1-ol2-(2-Iodophenyl)ethan-1-ol chemical name formula of 2-(2-Iodophenyl)ethan-1-ol
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label