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Structure of 259860-00-9
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2-Fluoro-4-methyl-5-nitroaniline features a strategically positioned nitro group that enhances electrophilic reactivity, while the fluorine substituent imparts electron-withdrawing character and metabolic stability. The methyl group provides steric modulation and influences regioselectivity in coupling reactions. This compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly where electron-deficient aromatic systems are required.
2-Fluoro-4-methyl-5-nitroaniline serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated heterocycles and bioactive scaffolds. Its electron-withdrawing nitro group and ortho-fluoro substituent facilitate directed metalation and subsequent functionalization. The compound exhibits good bench stability and compatibility with standard coupling reactions, simplifying purification and integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: