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CS-W001157 4
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3-Ethyl-7-(hydroxymethyl)-1,5-naphthyridin-2(1H)-one

  • CAS No. 2589531-74-6

  • Cat. No. CS-0256030
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Ethyl-7-(hydroxymethyl)-1,5-naphthyridin-2(1H)-one|CS-0256030

Structure of 2589531-74-6

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General Information

  • CAS No. 2589531-74-6
  • Cat. No. CS-0256030
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂N₂O₂
  • Molecular Weight 204.23
  • Synonym(s) None
  • SMILES O=C1NC2=CC(CO)=CN=C2C=C1CC

Description

3-Ethyl-7-(hydroxymethyl)-1,5-naphthyridin-2(1H)-one features a rigid naphthyridine core with complementary functional handles: an ethyl group enhancing lipophilicity and a hydroxymethyl moiety enabling downstream derivatization. This scaffold offers tunable solubility and stability under standard bench conditions, making it suitable for medicinal chemistry campaigns targeting kinase inhibitors and DNA-binding agents.

Application

3-Ethyl-7-(hydroxymethyl)-1,5-naphthyridin-2(1H)-one serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, enabling efficient derivatization at the hydroxymethyl and carbonyl functionalities. Its bench-stable nature and compatibility with standard coupling, oxidation, and protection protocols facilitate streamlined access to naphthyridine-based scaffolds relevant to kinase inhibitors and antiviral agents.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   65.98
  • LogP   0.9778
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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