H-D-Cys(Trt)-OH

Name: H-D-Cys(Trt)-OH
Brand: ChemScene
Availability: InStock
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CAS No. 25840-82-8
Cat. No. CS-0046195
Purity≥97%
MDL No.MFCD00236948

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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General Information

CAS No. 25840-82-8
Cat. No. CS-0046195
Purity ≥97%
MDL No. MFCD00236948
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₂H₂₁NO₂S
Molecular Weight 363.47
Synonym(s) None
SMILES OC([C@H](N)CSC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=O

Description

H-D-Cys(Trt)-OH is a bench-stable, moisture-tolerant D-amino acid derivative featuring a trifluoroacetyl-protected thiol side chain. This configuration enables direct incorporation into peptide sequences without racemization risk, streamlining synthesis of non-natural peptides for structural and functional studies.

Application

H-D-Cys(Trt)-OH serves as a stable, bench-ready building block for the synthesis of D-cysteine-containing peptides and thioether-linked architectures. The Trt (trityl) protecting group ensures orthogonal deprotection under mild acidic conditions, enabling selective cysteine side-chain manipulation. Its compatibility with standard Fmoc solid-phase peptide synthesis protocols facilitates efficient incorporation into complex peptide scaffolds, while maintaining stability during handling and purification.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 63.32
LogP 4.1236
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 7

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Cysteine and derivatives

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

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H-D-Cys(Trt)-OH

CAS No. 25840-82-8

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