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CS-W001157 4
Total: USD 88.00

5-Bromo-2-phenoxypyrimidine

  • CAS No. 257280-25-4

  • Cat. No. CS-0156074
  • Purity≥97%
  • MDL No.MFCD03646346

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-phenoxypyrimidine|CS-0156074

Structure of 257280-25-4

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General Information

  • CAS No. 257280-25-4
  • Cat. No. CS-0156074
  • Purity ≥97%
  • MDL No. MFCD03646346
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇BrN₂O
  • Molecular Weight 251.08
  • Synonym(s) Pyrimidine, 5-bromo-2-phenoxy-
  • SMILES C1=CC=C(C=C1)OC2=NC=C(C=N2)Br

Description

Reactant for: preparation of inhibitors of ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase as potential anticancer agents, N-Methylation reactions of the pyridyl group, Palladium catalyzed amination reactions, intramolecular Heck reactions, Coupling reactions and Synthesis of trisubstituted pyrimidines from polyhalopyrimidines via Suzuki coupling.

Synthesis

  • Route1

    References

    • CAYMAN CHEMICAL COMPANY Patent: US2010/75990 A1, 2010 ; Location in patent: Page/Page column 40 ;
  • Route2

    References

    • US2002/156081 A1, ; US 20020156081 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   35.01
  • LogP   3.0314
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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