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CS-W001157 4
Total: USD 88.00

1-Boc-4-(Cyanomethyl)piperidine

  • CAS No. 256411-39-9

  • Cat. No. CS-W003646
  • Purity≥97%
  • MDL No.MFCD09801019

*For research and further manufacturing use only, not for direct human use.

1-Boc-4-(Cyanomethyl)piperidine|CS-W003646

Structure of 256411-39-9

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General Information

  • CAS No. 256411-39-9
  • Cat. No. CS-W003646
  • Purity ≥97%
  • MDL No. MFCD09801019
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₀N₂O₂
  • Molecular Weight 224.30
  • Synonym(s) Tert-butyl 4-(cyanomethyl)piperidine-1-carboxylate
  • SMILES N#CCC1CCN(CC1)C(=O)OC(C)(C)C

Description

1-Boc-4-(Cyanomethyl)piperidine features a protected piperidine core with a cyanomethyl group at the 4-position, enabling direct incorporation into complex molecular architectures. The Boc group ensures stability during synthesis and facilitates selective deprotection under mild acidic conditions. This compound serves as a key building block for bioactive molecules in medicinal chemistry.

Application

1-Boc-4-(cyanomethyl)piperidine serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. The nitrile group enables downstream transformations such as amide formation, reduction to primary amines, or cyclization into pyrrolidinones. The Boc-protected piperidine core offers excellent bench stability and compatibility with standard coupling conditions, facilitating efficient functionalization and purification in multi-step synthetic sequences.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   53.33
  • LogP   2.54718
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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