Lot numbers can be found on the outside label of a product:
2-(4-Chloro-phenoxy)-phenylacetic acid
-
CAS No. 25563-04-6
- Cat. No. CS-B0045
- Purity≥98%
- MDL No.MFCD15528958
*For research and further manufacturing use only, not for direct human use.
Structure of 25563-04-6
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 25563-04-6
- Cat. No. CS-B0045
- Purity ≥98%
- MDL No. MFCD15528958
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₄H₁₁ClO₃
- Molecular Weight 262.69
- Synonym(s) None
- SMILES O=C(O)CC1=CC=CC=C1OC2=CC=C(Cl)C=C2
Description
2-(2-(4-Chlorophenoxy)phenyl)acetic acid features a rigid biphenyl scaffold linked by an ether bridge, delivering enhanced metabolic stability. The para-chloro substituent imparts electron-withdrawing character, while the acetic acid terminus enables facile derivatization. This compound serves as a key intermediate in synthesizing bioactive molecules with targeted pharmacological profiles.
Application
2-(2-(4-Chlorophenoxy)phenyl)acetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive arylacetic acid derivatives. Its structure features a chlorinated phenoxy moiety attached to a phenylacetic acid core, offering enhanced lipophilicity and metabolic stability. The carboxylic acid group facilitates straightforward derivatization via esterification, amidation, or salt formation, while the aromatic framework supports further functionalization through electrophilic substitution. This compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for high-throughput screening and lead optimization workflows.
Synthesis
-
Route1
-
1037313-34-0 - ~88%
-
In-stock
25563-04-6
References
-
Organon Ireland Ltd.; Pfizer Inc. Patent: US2006/229352 A1, 2006 ; Location in patent: Page/Page column 7-8 ;
-
-
Route2
-
In-stock
57486-69-8 -
106-48-9
- ~76%
-
In-stock
25563-04-6
References
-
Medichem, S.A. Patent: EP2468751 A2, 2012 ; Location in patent: Page/Page column 15-16 ;
-
-
Route3
-
In-stock
2444-36-2 -
106-48-9
- ~77%
-
In-stock
25563-04-6
References
-
MSN LABORATORIES LIMITED; SATYANARAYANA REDDY, Manne; THIRUMALAI RAJAN, Srinivasan; ESWARAIAH, Sajja; MADHU, Elevathingal Nicholas; SATYANARAYANA, Komati; SEETHA RAMA SARMA, Peri Patent: WO2012/38975 A2, 2012 ; Location in patent: Page/Page column 35 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H315-H319-H413
|
|
|
Precautionary Statements : P264-P273-P280-P302+P352-P362-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 46.53
- LogP 3.7594
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 4
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2-(4-Chloro-phenoxy)-phenylacetic acid sigma2-(4-Chloro-phenoxy)-phenylacetic acid manufacturer2-(4-Chloro-phenoxy)-phenylacetic acid price2-(4-Chloro-phenoxy)-phenylacetic acid structure2-(4-Chloro-phenoxy)-phenylacetic acid SDSbuy 2-(4-Chloro-phenoxy)-phenylacetic acid2-(4-Chloro-phenoxy)-phenylacetic acid supplier2-(4-Chloro-phenoxy)-phenylacetic acid uses2-(4-Chloro-phenoxy)-phenylacetic acid molecular weightprice of 2-(4-Chloro-phenoxy)-phenylacetic acid2-(4-Chloro-phenoxy)-phenylacetic acid chemical name formula of 2-(4-Chloro-phenoxy)-phenylacetic acid