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Boc-3,3-DicPr-Ala-OH

  • CAS No. 2548967-22-0

  • Cat. No. CS-0533685
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Boc-3,3-DicPr-Ala-OH|CS-0533685

Structure of 2548967-22-0

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General Information

  • CAS No. 2548967-22-0
  • Cat. No. CS-0533685
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₃NO₄
  • Molecular Weight 269.34
  • Synonym(s) None
  • SMILES C([C@H](NC(OC(C)(C)C)=O)C(O)=O)(C1CC1)C2CC2

Description

This chiral building block features a sterically encumbered dicyclopropyl substituent flanking a proline-like backbone, enabling precise control in peptide synthesis. The tert-butoxycarbonyl group provides orthogonal protection for amine functionalities, while the bench-stable, moisture-tolerant structure simplifies handling under standard conditions.

Application

(S)-2-((tert-Butoxycarbonyl)amino)-3,3-dicyclopropylpropanoic acid serves as a robust chiral building block for peptide and heterocyclic synthesis. The tert-butyl carbamate (Boc) group provides stable protection of the amine under acidic conditions, while the dicyclopropyl substituent enhances steric bulk and metabolic stability. Its bench-stable nature facilitates straightforward purification and compatibility with standard coupling protocols, enabling efficient access to complex scaffolds in medicinal chemistry campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.4005
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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