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(S)-2-((tert-Butoxycarbonyl)amino)-2-cycloheptylacetic acid

  • CAS No. 1228542-19-5

  • Cat. No. CS-0055760
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-2-((tert-Butoxycarbonyl)amino)-2-cycloheptylacetic acid|CS-0055760

Structure of 1228542-19-5

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General Information

  • CAS No. 1228542-19-5
  • Cat. No. CS-0055760
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₅NO₄
  • Molecular Weight 271.35
  • Synonym(s) (S)-2-(tert-butoxycarbonylamino)-2-cycloheptylacetic acid
  • SMILES O=C(O)[C@@H](NC(OC(C)(C)C)=O)C1CCCCCC1

Description

This chiral building block features a protected amino group and a cycloheptyl-bearing acetic acid side chain, enabling direct incorporation into peptide synthesis. The tert-butoxycarbonyl (Boc) group provides stability during coupling steps, while the sterically hindered cycloheptyl moiety enhances conformational rigidity in target structures.

Application

(S)-2-((tert-Butoxycarbonyl)amino)-2-cycloheptylacetic acid serves as a versatile chiral building block for the synthesis of cycloheptyl-containing amino acid derivatives. The Boc-protected amine and pendant carboxylic acid enable orthogonal functionalization, facilitating peptide coupling and downstream transformations. Its stability under standard reaction conditions supports reliable handling and purification, making it well-suited for medicinal chemistry campaigns requiring stereocontrolled access to complex scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.9347
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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