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Structure of 254749-11-6
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2-Chloro-4-cyanobenzene-1-sulfonyl chloride features a dual functional handle: a reactive sulfonyl chloride group and a para-cyano substituent. This combination enables efficient coupling in synthetic routes requiring electron-deficient aryl scaffolds, particularly in pharmaceutical intermediates and agrochemical development. The molecule exhibits enhanced stability under standard bench conditions.
2-Chloro-4-cyanobenzene-1-sulfonyl chloride serves as a versatile building block for sulfonamide-based scaffolds in medicinal chemistry. Its reactivity enables efficient coupling with amines to form sulfonyl amides under mild conditions, with the chloro and cyano groups offering orthogonal functionalization potential. Bench-stable and compatible with standard purification methods, it facilitates rapid access to diverse heterocyclic systems and API intermediates.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314-H317
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Precautionary Statements : P260-P261-P264-P272-P280-P301+P330+P331-P302+P352-P304+P340-P362+P364-P363-P405-P501
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Lot numbers can be found on the outside label of a product: