2-Cyano-5-methoxybenzene-1-sulfonyl chloride

Name: 2-Cyano-5-methoxybenzene-1-sulfonyl chloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1261573-04-9
Cat. No. CS-W021682
Molecule weight231.66
Purity≥97%
MDL No.MFCD18394209

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Cyano-5-methoxybenzene-1-sulfonyl chloride|CS-W021682

Structure of 1261573-04-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1261573-04-9
Cat. No. CS-W021682
Purity ≥97%
MDL No. MFCD18394209
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₆ClNO₃S
Molecular Weight 231.66
Synonym(s) None
SMILES O=S(C1=CC(OC)=CC=C1C#N)(Cl)=O

Description

2-Cyano-5-methoxybenzene-1-sulfonyl chloride features a sulfonyl chloride group flanked by a cyano and methoxy substituent, enabling selective functionalization in synthetic routes. The electron-withdrawing cyano enhances reactivity while the methoxy group provides steric and electronic modulation. This compound serves as a key intermediate in pharmaceutical and agrochemical synthesis, offering high stability under standard bench conditions and compatibility with diverse reaction media.

Application

2-Cyano-5-methoxybenzene-1-sulfonyl chloride serves as a versatile building block for sulfonamide synthesis, enabling efficient construction of bioactive heterocycles and pharmaceutical intermediates. Its ortho-cyano and meta-methoxy substituents provide enhanced solubility and modulate electronic properties, while the sulfonyl chloride group offers high reactivity in nucleophilic substitution reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for scalable medicinal chemistry applications and functional group interconversions in complex molecule assembly.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 3261
Class : 8	Packing Group : Ⅲ
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 67.16
LogP 1.49438
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

1261573-04-9 sigma1261573-04-9 manufacturer1261573-04-9 price1261573-04-9 structure1261573-04-9 SDSbuy 1261573-04-91261573-04-9 supplier1261573-04-9 uses1261573-04-9 molecular weightprice of 1261573-04-91261573-04-9 chemical name formula of 1261573-04-9

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Cyano-5-methoxybenzene-1-sulfonyl chloride

CAS No. 1261573-04-9

Recommended Products