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Structure of 254732-51-9
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2-Chloro-3-(trifluoromethyl)quinoxaline is a bench-stable heterocyclic building block featuring a chlorine atom at the 2-position and a trifluoromethyl group at the 3-position, enabling selective cross-coupling reactions. This electron-deficient quinoxaline integrates efficiently into pharmaceutical scaffolds and functional materials, offering enhanced metabolic stability and tunable electronic properties through its fluorinated substituent.
2-Chloro-3-(trifluoromethyl)quinoxaline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its electrophilic chlorine and electron-deficient quinoxaline core. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the compound exhibits bench stability and compatibility with standard reaction conditions. It functions effectively in Suzuki-Miyaura, Stille, and Buchwald-Hartwig couplings, facilitating rapid access to diverse heterocyclic scaffolds for API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: