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Structure of 253176-94-2
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tert-Butyl 3-(iodomethyl)azetidine-1-carboxylate features a reactive iodomethyl group on a strained azetidine ring, enabling efficient alkylation under mild conditions. This bench-stable reagent integrates readily into complex molecular architectures, offering high functional group tolerance and compatibility with diverse synthetic transformations in medicinal chemistry and chemical biology applications.
tert-Butyl 3-(iodomethyl)azetidine-1-carboxylate serves as a versatile building block for constructing azetidine-containing scaffolds in medicinal chemistry. The iodoalkyl group enables efficient SN2-mediated functionalization, while the tert-butyl carbamate protects the nitrogen under standard conditions. Its bench-stable nature and compatibility with palladium-catalyzed cross-coupling reactions facilitate rapid diversification of azetidine cores in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: