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CS-W001157 4
Total: USD 88.00

NH2-PEG3-C2-Boc

  • CAS No. 252881-74-6

  • Cat. No. CS-0114210
  • Purity≥97%
  • MDL No.MFCD06201017

*For research and further manufacturing use only, not for direct human use.

NH2-PEG3-C2-Boc|CS-0114210

Structure of 252881-74-6

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General Information

  • CAS No. 252881-74-6
  • Cat. No. CS-0114210
  • Purity ≥97%
  • MDL No. MFCD06201017
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₇NO₅
  • Molecular Weight 277.36
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCOCCOCCN

Description

Nicotinamide (NAM) belongs to vitamin B family and is the amide form of vitamin B3. NAM is present in food and is a constituent of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). Tryptophan is the precursor for NAM synthesis in liver. NAM controls cell metabolism, redox reactions, mitochondrial functionsand energy generation. It promotes natural killer cells proliferation and survival. NAM confers neuroprotection and promotes neuronal maturation. It has the ability to cross the blood-brain barrier and may provide protection in ischaemic stroke and traumatic brain injury. NAM may elicit therapeutic benefits in Alzheimers, Parkinsons, and Huntingtons diseases.Nicotinamide has been used as a medium supplement in organoid culture of intestinal stem cells, esophageal squamous cell carcinomas(ESCC), pancreatic cancer organoids and pancreatic progenitor induction.

Synthesis

  • Route1

    References

    • US2006/205670 A1, ; Page/Page column 105 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   80.01
  • LogP   0.7267
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   11

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