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Amino-PEG1-C2-acid

  • CAS No. 144942-89-2

  • Cat. No. CS-0114519
  • Purity≥98%
  • MDL No.MFCD22017475

*For research and further manufacturing use only, not for direct human use.

Amino-PEG1-C2-acid|CS-0114519

Structure of 144942-89-2

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General Information

  • CAS No. 144942-89-2
  • Cat. No. CS-0114519
  • Purity ≥98%
  • MDL No. MFCD22017475
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO₃
  • Molecular Weight 133.15
  • Synonym(s) None
  • SMILES O=C(O)CCOCCN

Description

Amino-PEG1-C2-acid features a terminal amine and carboxylic acid group separated by a short ethylene glycol chain, enabling dual conjugation versatility. This bifunctional linker supports efficient coupling to biomolecules or surfaces via amine- or carboxyl-reactive chemistries. The PEG spacer enhances solubility and reduces non-specific binding in biological applications.

Application

Amino-PEG1-C2-acid serves as a versatile bifunctional linker for conjugation and polymer synthesis. The primary amine enables efficient coupling to carboxylate- or aldehyde-functionalized substrates, while the terminal carboxylic acid facilitates amide bond formation or activation with common coupling reagents. Its PEG1 spacer provides moderate hydrophilicity and solubility in aqueous and organic media, enhancing compatibility in bioconjugation workflows. The molecule exhibits excellent bench stability and simplifies purification by enabling selective derivatization under standard conditions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.55
  • LogP   -0.5636
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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