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CS-W001157 4
Total: USD 88.00

3'-Amino-3'-deoxyadenosine

  • CAS No. 2504-55-4

  • Cat. No. CS-0141378
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD28342915

*For research and further manufacturing use only, not for direct human use.

3'-Amino-3'-deoxyadenosine|CS-0141378

Structure of 2504-55-4

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General Information

  • CAS No. 2504-55-4
  • Cat. No. CS-0141378
  • Purity ≥97%
  • MDL No. MFCD28342915
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄N₆O₃
  • Molecular Weight None
  • Synonym(s) None
  • SMILES NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](N)[C@@H](CO)O3

Description

3'-Amino-3'-deoxyadenosine features a nucleobase scaffold with a primary amine at the 3' position, replacing the hydroxyl group. This modification enhances solubility and stability in aqueous media while preserving recognition by polymerases. The compound serves as a key building block for site-specific incorporation into oligonucleotides, enabling applications in probe design, chemical biology, and synthetic genetics.

Synthesis

  • Route1
    • 3'-(Benzylamino)-3'-deoxyadenosine|CS-D0377
      67313-10-4
    • ~10%
    • In-stock
      3'-Amino-3'-deoxyadenosine|CS-0141378
      2504-55-4

    References

    • Samano; Robins Tetrahedron Letters, 1989 , vol. 30, # 18 p. 2329 - 2332
  • Route2

    References

    • Botta, Oliver; Moyroud, Elisabeth; Lobato, Cinta; Strazewski, Peter Tetrahedron, 1998 , vol. 54, # 44 p. 13529 - 13546
  • Route3
    • null|null
      125084-68-6
    • ~%
    • In-stock
      3'-Amino-3'-deoxyadenosine|CS-0141378
      2504-55-4

    References

    • Zhang, Lei; Cui, Zhiyong; Zhang, Biliang Helvetica Chimica Acta, 2003 , vol. 86, # 3 p. 703 - 710

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   145.33
  • LogP   -2.0136
  • H_Acceptors   9
  • H_Donors   4
  • Rotatable_Bonds   2

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