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Structure of 249291-79-0
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6-Chloro-3-iodo-2-methylpyridine is a halogenated pyridine derivative featuring complementary reactive sites for cross-coupling and functionalization. The chloro group enables palladium-catalyzed coupling, while the iodide facilitates efficient transition-metal-mediated transformations. This molecule integrates readily into complex heterocyclic scaffolds under mild conditions.
6-Chloro-3-iodo-2-methylpyridine serves as a versatile building block in cross-coupling chemistry, enabling efficient construction of substituted pyridine scaffolds. The orthogonal halogenation pattern facilitates sequential Pd-catalyzed coupling reactions, with the chlorine site suitable for Buchwald–Hartwig amination and the iodide position amenable to Suzuki or Negishi couplings. Its bench-stable nature and predictable reactivity make it ideal for iterative synthesis of complex heterocycles in medicinal chemistry and agrochemical development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: