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CS-W001157 4
Total: USD 88.00

N-Formylglycine

  • CAS No. 2491-15-8

  • Cat. No. CS-0102520
  • Purity≥95%
  • MDL No.MFCD00037360

*For research and further manufacturing use only, not for direct human use.

N-Formylglycine|CS-0102520

Structure of 2491-15-8

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General Information

  • CAS No. 2491-15-8
  • Cat. No. CS-0102520
  • Purity ≥95%
  • MDL No. MFCD00037360
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₅NO₃
  • Molecular Weight 103.08
  • Synonym(s) None
  • SMILES O=C(O)CNC=O

Description

N-Formylglycine delivers a unique aldehyde functionality essential for site-specific bioconjugation. This bench-stable derivative of glycine features a formyl group at the nitrogen, enabling selective coupling with hydrazides and amines under physiological conditions. The molecule integrates seamlessly into peptide synthesis workflows, offering high chemoselectivity and minimal side reactions.

Synthesis

  • Route1
    • null|null
      64-18-6
    • Glycine, 99%|CS-1269057
      56-40-6
    • ~98%
    • In-stock
      N-Formylglycine|CS-0102520
      2491-15-8

    References

    • Aizpurua, Jezus Mari; Palomo, Claudio Synthetic Communications, 1983 , vol. 13, # 9 p. 745 - 752
  • Route2
    • null|null
      51354-16-6
    • ~94%
    • In-stock
      N-Formylglycine|CS-0102520
      2491-15-8

    References

    • Du, Zuyin; Yanhui, Lu; Dai, Xuedong; Zhang-Negrerie, Daisy; Gao, Qingzhi Journal of Chemical Research, 2013 , vol. 37, # 3 p. 181 - 185
  • Route3
    • null|null
      128038-38-0
    • ~71%
    • In-stock
      N-Formylglycine|CS-0102520
      2491-15-8

    References

    • Yinglin, Han; Hongwen, Hu Synthesis, 1990 , # 2 p. 122 - 124

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.4
  • LogP   -1.183
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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